An Antibacterial Potential of Cerium Oxide Nanoparticles against Mycobacterium tuberculosis: A Novel Approach for Tuberculosis Treatment

Authors

  • S. A. Noonari Mechanical Engineering Department Isra University Hyderabad
  • M. Gul MERE IBA university sukkur
  • J. Ali Department of Environmental Sciences University of Sindh Jamshoro
  • H. A. Khan Mechanical Engineering Department Isra university Hyderabad
  • F. Mustafa Department of Mechanical Engineering QUEST Nawabshah

DOI:

https://doi.org/10.71330/thenucleus.2025.1460

Abstract

This study investigated the antibacterial effects of cerium oxide nanoparticles (CON) on Mycobacterium tuberculosis. Cerium oxide nanoparticles were synthesised using a microwave-induced technique and characterized by Scanning Electron Microscopy. Results indicated that an increase in synthesis time led to a reduction in nanoparticle size, demonstrating that the duration of the synthesis process influenced particle size. Additionally, the antibacterial activity of CON particles was found to be size-dependent. In a disc diffusion assay, cerium oxide nanoparticles enhanced the efficacy of antibacterial agents, significantly improving the effectiveness against Terivid, Amikin, Grasil, Velosef, Spraxin, and Ceftriaxone against Mycobacterium tuberculosis.

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Published

04-08-2025

How to Cite

[1]
S. A. Noonari, M. Gul, J. Ali, H. A. Khan, and F. Mustafa, “An Antibacterial Potential of Cerium Oxide Nanoparticles against Mycobacterium tuberculosis: A Novel Approach for Tuberculosis Treatment”, The Nucleus, vol. 62, no. 2, pp. 65–68, Aug. 2025.

Issue

Vol. 62 No. 2 (2025)

Section

Articles

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