STRUCTURAL ELUCIDATION OF TRANSITION METAL COMPLEXES OF MODIFIED DIAMINE ALONGWITH BIOASSAY STUDIES
DOI:
https://doi.org/10.71330/thenucleus.2009.927Abstract
A number of complexes of modified diamine (3,7-dimethyl-1,5-dithia-3,7-diazacyclooctane), were prepared with first row divalent transition metals, i.e., Cu(II) and Zn(II). The structures of these complexes were elucidated on the basis of various physical techniques such as mass spectrometry, NMR, IR, UV-Visible spectroscopies, magnetic and conductance measurements. Bioassay of these complexes has also been carried out. The physical measurements confirm distorted tetrahedral structure for these complexes.References
P. J. Hendra and D. B. Powel, J. Chem. Soc.,
(1960) 5105.
F.G. Mann and H. R. Watson, J. Chem. Soc.,
(1958) 2772.
W. K. Musker and M. S. Hussain, Inorg.
Chem. 5, No. 8 (1966) 1416.
W. K. Musker and M. S. Hussain, Inorg.
Chem. 8, No. 3 (1969) 528.
D. O. Nielson, M. L. Larson, D.L. Smith and
J.I. Legg, J. Am. Chem. Soc. 90, No. 18
(1968) 5030.
M. S. Hussain and Saeed-ur-Rehman, Z.
Naturforsch. 33b (1978) 67.
M. S. Hussain and Saeed-ur-Rehman, Inorg.
Chimica Acta 60 (1982) 233.
(a) C. Hoose, K. Eberhardt, W. Hartmann
and W. Wosniok, Pneumologie. 44, No. 1
(1990) 458. (b) V. N. Saliaev, N. S. Titov and
V.P. Ermolaev, Farmakol Toksikol. 43, No. 4
(1980) 327.
H. Vidrio, G. Fernandez, M. Medina, E.
Alvarez and F. Orallo, Vascul.Phamacol. 40,
No. 1 (2003) 13.
J. Delaney and J. A. Timbrell, Xenobiotica
, No. 12 (1995) 1399.
W. D. MacRae and H. F. Stich, Mutat. Res.
, No. 4 (1979) 35.
M. Strolin-Benedetti and K. F. Tipton, J.
Neural Transm.Suppl. 52 (1998) 149.
S.R. Saunders and W. Karo, Organic
Functional Groups, Academic Press New
York & London (1968) pp. 363-384.
B.S. Holla, M. Mahalinga, M. S. Karthikeyan,
B. Poojary and P.M. Akber Ali, European
Journal of Medicinal Chemistry 40, No. 11
(2005) 1173.
B.N. Figgis, J. Lewis and R.G. Wikins, (Eds),
Modern Coordination Chemistry, Interscience, New York (1960) p. 412.
R. Chang, Physical Chemistry for the
Biosciences, University Science Books,
(2005) p. 482.
R. R. Roe and Yuan-Ping Pang, J. Mol.
Model. 5 (1999) 134.
B. Trzaskowski, L. Adamowicz and P.A.
Deymier, J. Biol. Inorg. Chem. 13 (2008) 133.
T. Dudev and C. Lim, J. Am. Chem. Soc. 122
(2000) 11146.
E. Meggers, Current Opinion in Chemical
Biology 11, No. 3 (2007) 287.
Vrednye veshchestva v promyshlennosti.
Spravochnik (Noxious Substances in
Industry: A Handbook), Lazarev, N.V., Ed.,
Leningrad: Khimiya, 1, 2 (1965)
Atta-ur-Rahman, M.I. Choudhary and W.J.
Thomsen, Bioassay Techniques for Drug
Development. Amsterdam, The Netherlands:
Harwood Academic, 2001.
Downloads
Published
How to Cite
Issue
Section
License
For all articles published in The Nucleus, copyright is retained by the authors. Articles are licensed under an open access licence [CC Attribution 4.0] meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited properly.
