The Nucleus http://202.83.167.189/index.php/Nucleus <p><em>The Nucleus</em> is a well-established, open-access, peer-reviewed multidisciplinary scientific journal that has been in publication since 1964. The journal offers free access to all its content, both electronically and in print, ensuring that research is widely available to the public without any cost barriers. It is accredited as Y-category journal by the Higher Education Commission (HEC), and published biannually. <em>The Nucleus</em> invites research scholars, faculty members, and academicians from various disciplines, particularly in the natural and applied sciences, to submit their original research manuscripts. The journal is committed to promoting flawless and unbiased research, adhering to international publishing standards. The publisher also actively promotes published articles worldwide through various media channels, in line with open access regulations, ensuring that the research reaches a broad audience.</p> <p>The motto of <em>The Nucleus</em> reflects its dedication to transparency, integrity, and the promotion of high-quality research.</p> <p><strong><!--a href='#' id="fullscope" >Read More >></a--></strong></p> en-US <p>For all articles published in <em>The Nucleus</em>, copyright is retained by the authors. Articles are licensed under an open access licence <a href="https://creativecommons.org/licenses/by/4.0/" target="_blank" rel="noopener">[CC Attribution 4.0]</a> meaning that anyone may download and read the paper for free. In addition, the article may be reused and quoted provided that the original published version is cited properly.</p> editorinchief@thenucleuspak.org.pk (Dr. Maaz Khan (Editor-in-Chief)) editorialoffice@thenucleuspak.org.pk (Mr. Touseef Tufail (Editorial Assistant)) Mon, 14 Jul 2025 10:32:58 +0500 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Deep Q Networks for Classification: Performance Analysis on Iris and Diabetes Datasets http://202.83.167.189/index.php/Nucleus/article/view/1461 <p class="NuclAbstract">This study explores how Deep Q Networks (DQNS) can be applied to classifying data with standard datasets. Though DQNs are designed for sequential decisions, this study uses the Iris and Diabetes datasets, which are both used for classification, to test the performance. It investigates DQNs with different data imbalances and compares their results based on the quantity of data. Models are assessed using accuracy, precision, recall, F1 score, ROC-AUC, the amount of memory required, and their training speed. As demonstrated by the results, DQNs can match other algorithms in accuracy while attaining accuracy rates between 84% and 95% for various datasets and modified configurations. Based on the study, performance can be affected by adjusting hyperparameters and the distribution of data classes. DQNs are more complex than common classifiers such as SVMs and decision trees, and their main contribution in simple classification is yet to be proven. It adds to the enthusiasm for using reinforcement learning models in the context of supervised learning. The paper highlights the value of correct evaluation, points out risks linked to model over-fitting and includes new areas to pursue in the future such as benchmarking, clarifying models and using hybrid systems.</p> M. Rehman, M. Baig Copyright (c) 2025 The Nucleus https://creativecommons.org/licenses/by/4.0 http://202.83.167.189/index.php/Nucleus/article/view/1461 Mon, 14 Jul 2025 00:00:00 +0500 An Antibacterial Potential of Cerium Oxide Nanoparticles against Mycobacterium tuberculosis: A Novel Approach for Tuberculosis Treatment http://202.83.167.189/index.php/Nucleus/article/view/1460 <p>This study investigated the antibacterial effects of cerium oxide nanoparticles (CON) on Mycobacterium tuberculosis. Cerium oxide nanoparticles were synthesised using a microwave-induced technique and characterized by Scanning Electron Microscopy. Results indicated that an increase in synthesis time led to a reduction in nanoparticle size, demonstrating that the duration of the synthesis process influenced particle size. Additionally, the antibacterial activity of CON particles was found to be size-dependent. In a disc diffusion assay, cerium oxide nanoparticles enhanced the efficacy of antibacterial agents, significantly improving the effectiveness against Terivid, Amikin, Grasil, Velosef, Spraxin, and Ceftriaxone against Mycobacterium tuberculosis.</p> S. A. Noonari, M. Gul, J. Ali, H. A. Khan, F. Mustafa Copyright (c) 2025 The Nucleus https://creativecommons.org/licenses/by/4.0 http://202.83.167.189/index.php/Nucleus/article/view/1460 Mon, 04 Aug 2025 00:00:00 +0500 Laser-Induced Breakdown Spectroscopy in Vegetable Analysis: Contaminants and Nutrients http://202.83.167.189/index.php/Nucleus/article/view/1479 <p class="NuclAbstract">Vegetables are rich in minerals, but pollutants and wastewater, which introduce heavy metals into the soil, heavily impact their cultivation. As an efficient and effective methodology, scientists prefer using Laser-Induced Breakdown Spectroscopy (LIBS) as a light-based technique to determine the elemental constituents of vegetables. It aids in safety and quality assurance by allowing them to image nutrients and hazardous metals, such as cadmium. This study explored the application of LIBS for detecting contaminants, such as Cd, and profiling essential nutrients in vegetables. Unlike conventional methods such as ICP-MS and AAS, LIBS offers fast, on-site, and multi-element analyses with minimal sample preparation. This review consolidates recent studies on carrots, potatoes, spinach, broccoli, and other leafy greens, emphasizing enhancements using nanoparticles and chemometric tools to improve sensitivity and accuracy. According to the results, LIBS has also been effectively employed to analyze the components of vegetables, enhancing the control and safety of food quality surveillance. The results also prove that LIBS can be a better method for monitoring food quality and safety. LIBS is more consumer-and environmentally friendly because it is portable, fast, and capable of simultaneously analyzing various components.</p> A. Anwar, A. Rashid, M. Rashid Copyright (c) 2025 The Nucleus https://creativecommons.org/licenses/by/4.0 http://202.83.167.189/index.php/Nucleus/article/view/1479 Mon, 15 Sep 2025 00:00:00 +0500